The Vaccine Research Hub (VRH) provides a coordinated, comprehensive approach to the full vaccine value chain as is primarily relevant to South African requirements, with a broader lens of the African health catchment.
The Vaccine Research Hub (VRH) provides a coordinated, comprehensive approach to the full vaccine value chain as is primarily relevant to South African requirements, with a broader lens of the African health catchment. To be comprehensive, the VRH develops competence for all vaccine platforms and antigen candidates, but with a focus on newer technologies and vaccines relevant to regional pandemic disease. The VRH is scientist-directed and structured as a Centre within the University of Witwatersrand (Wits), operating as a Division within Wits Health Consortium (WHC), a wholly owned company of Wits. The VRH is directed by a Scientific Board with Professor Shabir Madhi (Professor of Vaccinology) as Chair, with an Executive Committee charged with the daily VRH operations.
Dyadic International, Inc. is a global biotechnology company focused on deploying its proprietary C1-cell protein production platform to accelerate development, lower production costs and improve the performance of biologic vaccines and drugs. Dyadic International, Inc. has developed its gene expression platform based on the fungus Thermothelomyces heterothallica (formerly Myceliophthora thermophila), named C1. The C1 microorganism, which enables the development and large-scale manufacture of low-cost proteins, has the potential to be further developed into a safe and efficient expression system that may help speed up the development, lower production costs and improve the performance of biologic vaccines and drugs at flexible commercial scales. RUBIC One Health and Dyadic International, Inc. have partnered to further develop the C-1 cell protein production platform for use in developing and manufacturing safe and effective vaccines. If successful, such vaccines can be manufactured rapidly and affordably, in very large quantities.
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